September 19-21, 2004
Midtown Executive Club
New York City, NY
6:00 - 6:45 Welcoming Reception (no host bar).
6:45 - 7:00 Steve Cummings: Welcoming remarks and report on the Longevity Consortium
Grant
7:00 - 8:00 BUFFET DINNER
8:00 - 8:45 After-Dinner Presentation: Kristen Hawkes, "Grandmothers and
the evolution of
human longevity"
8:45 - 9:00 Group Discussion
Day One, September 20 Location: Midtown Executive Club
The Role of Genetic Imprinting and Epigenetics in Disease Risk and Mortality
Morning Sessions led by Arnie Kahn
8:30 - 9:00 Sue Ozanne, "Thrifty phenotype hypothesis and effect of pre-
and early
postnatal nutrition on the insulin pathway and longevity"
9:00 - 9:20 Questions and Discussion
9:20 - 9:40 Randy Jirtle, "Imprinted genes and transposons: Epigenomic
targets linking
prenatal nutrition to adult disease susceptibility"
9:40 - 10:10 Questions and Discussion
10:10-10:30 AM Break
Inflammation, Cytokines and Aging (10:30-12:15 AM)
10:30 - 11:00 William Ershler, "The role of inflammation (inflammatory)
cytokines in late-life
diseases and frailty"
11:00 - 11:20 Questions and Discussion
11:20 - 12:10 Alex Reiner, "Inflammation and the risk of cardiovascular
disease"
12:10 - 12:30 Questions and Discussion
¤12:30-2:00 PM Lunch Break (everyone on their own to enjoy NYC)
Stem Cells, Cancer and Aging (Senescence) of the Organism
Afternoon Sessions led by Warren Browner
2:00 - 2:30 Judy Campisi, "Cancer and aging: yin, yang, and p53"
2:30 - 2:50 Questions and Discussion
2:50 - 3:20 Heidi Scrable, "Modulation of mammalian life span by the short
isoform of p53"
3:20 - 3:40 Questions and Discussion
3:40 - 4:10 Larry Donehower, "p53 and the regulation of stem cell pools"
4:10 - 4:30 Questions and Discussion
4:45 - 5:30 Steve Cummings et al. "Progress report and future scientific directions"
No group dinner is planned for this evening.
Day Two, September 21
Today's Session led by Steve Cummings:Antioxidants and Longevity:
8:30 - 9:00 John Tower, "Mechanism of life span extension by Drosophila
MnSOD"
9:00 - 9:20 Questions and discussion.
Progress Reports:
Research on Centenarians
9:20 - 9:35 Tom Perls, "Recent findings from the New England Centenarian
Study (availability of DNA for Collaboration)"
9:30 - 9:45 Questions and discussion
9:45 - 10:15 Lara Terry, "Offspring of Centenarians as a Model of Successful
Aging"
10:15 - 10:25 Questions and discussion
10:25 - 10:40 Nir Barzilai, "Conserved DAF-16/FOXO Pathway for Exceptional
Longevity in Humans"
10:40 - 10:55 Questions and discussion
10:55-11:10 Coffee Break
Other Presentations
11:10 - 11:25 Cornelia Van Duijn, "Genotyping HSP alleles in aging human
cohorts"
11:25 - 11:35 Questions and discussion
11:35 - 11:50 Andrzej Barkte, "SIRT1, caloric restriction, and longevity
in mice"
11:50 - 12:00 Questions and discussion
12:00 - 12:15 Elad Ziv, "Admixture, cardiovascular disease-related phenotypes
among
African Americans in CHS"
12:15 - 12:25 Questions and discussion
12:25 - 12:40 Yousin Suh, "SNP screening in aging"
12:40 - 12:50 Questions and discussion
12:50 - 1:00 Meeting Closes/ Final Remarks