October 25-27, 2006
Embassy Suites Hotel
Napa, CA
October 25, 2006 Meeting Room: Chardonnay Bc
6:00pm Opening Reception at the Fountain Court (No Host Bar)
6:45pm - 7:00pm Steve Cummings: Welcoming remarks
7:00pm - 8:00pm Reception Dinner
AFTER DINNER PRESENTATION
8:00pm - 8:45pm Tim Spector: Insights on aging from The Study Of Twins
8:45pm - 9:00pm Group Discussion
October 26, 2006 Meeting Room: Chardonnay Ab
7:00am - 8:00am Breakfast at the Atrium
SESSION ONE: MITOCHONDRIA, AGING AND LONGEVITY
8:00am - 8:40am Tomas Prolla: Mitochondrial DNA mutations, oxidative stress and apoptosis in mammalian aging
8:40am - 9:20am David Rand: Nuclear-mitochondrial epistasis and aging
9:20am - 10:00am Janine Santos: Telomerase and mitochondrial quality control
10:00am - 10:20am Coffee Break
10:20am - 10:50am Greg Tranah: Opportunity fund proposal on mitochondrial DNA mutations and human longevity
SESSION TWO: PLENARY PRESENTATION
10:50am - 11:30am Eric Ravussin: Caloric restriction in humans: The Calarie Study
11:30am - 1:00pm Buffet Lunch at the Atrium
11:30am - 1:00pm Steering Committee and OSMB Luncheon Meeting
SESSION THREE: HEAT SHOCK PROTEINS, MOLECULAR CHAPERONES, AGING AND LONGEVITY
1:00pm - 1:40pm Cindy Voisine: Monitoring protein homeostasis in c elegans polyglutamine disease models
1:40pm - 2:20pm Gordon Lithgow: Heat shock proteins in aging and longevity in c elegans
SESSION FOUR: PROJECT PROGRESS REPORTS - I
2:20pm - 2:50pm Richard Miller: Genetics of stress resistance and aging in mice
2:50pm - 3:10pm Coffee Break
3:10pm - 3:40pm Wen-Chi Hsueh and Richard Cawthon: The role of telomeres in human longevity and aging
SESSION FIVE: NEW APPROACHES IN LONGEVITY RESEARCH
3:40pm - 4:20pm Michelle Boehm: A developmental timing microrna and its target regulate life span in c elegans
4:20pm - 5:00pm Ben Van Houten: Altered homeostatic networks and decreased nucleotide excision repair in aging c elegans
Dinner (on your own)
WGA MEETING MEETING ROOM: BOARDROOM
October 27, 2006 Meeting Room: Chardonnay Ab
7:00am - 8:00am Breakfast at The Atrium
8:00am - 8:20am Steve Cummings: Status report on The Longevity Consortium
SESSION SIX: PROJECT PROGRESS REPORTS - II
8:20am - 8:50am Elad Ziv: Insulin/ Igf-1 signaling pathway genes and human longevity
8:50am - 9:20am Andrzej Bartke and Michal Masternak: insulin signaling gene expression in long-lived mice
SESSION SEVEN: DNA METHYLATION AND NUCLEAR PROTEINS IN AGING
9:20am - 10:00am Jean-Pierre Issa: Epigenetics, cancer and aging
10:00am - 10:40am Colin Stewart: Aging and nuclear organization
10:40am - 11:00am Coffee Break
11:00am - 11:40am Judy Campisi: The regulation of cellular senescence by nuclear proteins
11:40am - 12:20pm Heidi Tissenbaum: Chromatin immunoprecipitation in the identification of genes controlling longevity and metabolism
SESSION EIGHT: GENOME SCANS AND HUMAN AGING (New Initiative)
12:20pm - 1:00pm Joanne Murabito and Kathryn Lunetta: A first look at aging phenotypes and 100k genome-wide results in The Framingham Heart Study
1:00pm Boxed Lunch at the Atrium (to go)