November 28-30, 2005
Marriott San Diego GasLamp Quarter
San Diego, CA
November 28 Day One- Evening Opening Session
6:00pm Opening Reception (no host bar)
6:45pm Steve Cummings: Welcoming Remarks
7:00pm Group Dinner
AFTER DINNER PRESENTATION
7:45- 9:00pm George Martin: Gene actions that escape the force of natural selection
November 29 Day Two- All Day Meeting
7:30- 8:15am Continental Breakfast
SESSION ONE: THE (XENO)HORMESIS HYPOTHESIS; LOW LEVEL STRESS AS A LONGEVITY EXTENDER
8:15- 9:00am Joseph Baur: Toward a unified theory of caloric restriction and longevity regulation
9:00- 9:45am Greg Tranah and Joseph Baur: Role of Sirtuins in human longevity
9:45- 10:15am Coffee Break
SESSION TWO: THE INSULIN PATHWAY, NUTRIENT SENSING AND LIFE SPAN
10:15- 11:00am Pankal Kapahi:TOR pathway, longevity and metabolism
11:00- 11:45am Makota Kuro-o: Significant longevity extension in mice by klotho peptide
11:45- 1:30pm Lunch (on your own) --- Steering Committee Lunch Meeting
SESSION THREE: INTERVENTIONS LEADING TO INCREASED LONGEVITY
1:30- 2:15pm Gordon Lithgow: High throughput screening of C elegans for compounds that extend longevity; effect of lithium
2:15- 3:00pm Kerry Kornfeld: Anticonvulsants and lifespan extension in C elegans
3:00- 3:15pm Coffee Break
3:30- 4:15pm C David Rollo: Complex dietary interventions improve longevity and cognitive function in growth hormone transgenic mice
4:15- 5:00pm Laura Dugan: Carboxyfullerenes as anti-aging/ anti-neurodegenerative therapeutics
Dinner (on your own)
November 30, 2005 Day Three - All Day Meeting
7:15- 8:00am Continental Breakfast
SESSION FOUR: PROJECT UPDATE REPORTS
8:00- 8:30am Alex Reiner: Stress, Inflammation, and Genetics of Human Longevity
8:30- 9:00am Elad Ziv: Insulin/IGF-1 Signaling Pathway Genes and Human Longevity
9:00- 9:30am Andrezj Bartke: Insulin Signaling Gene Expression in Long-lived Mice
9:30- 9:45am Coffee Break
9:45 -10:15am Richard Cawthon: The Role of Telomeres in Human Longevity and Aging
10:15- 11:00am Abraham Aviv: Telomeres and the human life span: gender, genes and the disposable soma
SESSION FIVE: WHOLE GENOME ANALYSIS - REVIEW AND POSSIBLE APPLICATION
11:00- 11:45am Dietrich Stephan: Whole genome SNP association scanning to detect allelic variants correlated to a trait
11:45- 12:30pm Bradley Willcox and Wen-Chi Hsueh: Whole genome analysis in Okinawan Centenarians
12:30- 1:30pm Lunch (on your own)
SESSION SIX: BIOSTATISTICAL METHODS IN GENETICS
1:30- 2:10pm Anna Di Rienzo: Evolutionary analysis of candidate genes
2:10- 2:35pm Charles Kooperberg: Gene x gene interactions
2:35- 3:00pm Indrani Halder: AIMs and population substructure
3:00- 3:25pm Alex Reiner: Genetic networks and candidate genes
3:25- 3:40pm Coffee Break
3:40- 4:05pm Anatoly Yashin: The use of ancillary information
4:05- 4:30pm Hongze Li: Phenotype definitions and analysis
4:30- 4:55pm Nicholas Schork: Multivariate analysis
4:55pm Steve Cummings: Closing Remarks