February 27 - March 1, 2005
Cathedral Hill Hotel
San Francisco, CA

6:00 - 6:45 Welcoming Reception (no host bar).
6:45 - 7:00 Steve Cummings: Welcoming remarks

7:00 - 8:00 GROUP DINNER

8:00 - 8:45 After-Dinner Presentation
8:45 - 9:00 Group Discussion


Day One, February 28

Session One: The Genetics of Alzheimer's Disease

8:15 - 9:00 Lars Betram: Alzheimer's disease: one disorder, too many genes?

9:00 - 10:45 Cornelia van Duijn: Familial clustering and genetic risk for dementia (in a genetically isolated Dutch population).

10:45-11:00 AM Break

11:00 - 11:45 Andrey Rzhetsky: Molecular triangulation: Bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease

11:45 - 12:00 Discussion - Alzheimer's disease: Can it serve as a paradigm for studies of the genetics of human physiological aging?

12:00- 1:30 Lunch (on your own)

Session Two: The Genetics of Human Aging

1:30 - 2:45 Stuart Kim: Functional genomics of human aging

2:45 - 3:30 Joao P de Magalhaes: How genomes regulate aging: a systems-level approach to the genetics of aging.

3:39 - 3:45 Coffee Break


Session Three: DNA Damage, Repair and the Aging Process

3:45 - 4:30 Judy Campisi: DNA damage responses and normal and premature aging phenotypes

4:30 - 5:15 TBA

5:15 - 5:30Steve Cummings: STATUS REPORT ON THE LONGEVITY CONSORTIUM


Day Two, March 1

Session Four: Pilot Projects

8:15 - 8:45 Lara Terry: Telomere shortening in long-lived Humans

8:45 - 9:15 Cornelia Van Duijn: Genetic variation in HSPs and human longevity

9:45 - 10:15 Yousin Suh: SNP Screening in aging

10:15 - 10:30 Coffee Break

10:30 - 11:00 Peggy Cawthon: Histone deacetylases and human aging

11:00 - Noon Other proposals

Noon Meeting Closes/ Final Remarks