Dec 2-3, 2007
Georgetown Room, Hyatt Hotel
Bethesda, Maryland


Consortium Program and Research Activities


Sunday, December 2, 2007

Meeting Participants Arrive

December 3, 2007 - Georgetown Room

7:30am - 8:30am Breakfast


SESSION ONE: THE ANATOMY AND PHYSIOLOGY OF THE LONGEVITY CONSORTIUM


8:30am - 8:35am Richard Hodes: Opening Remarks

8:35am - 8:45am Steve Cummings: Overview of Longevity Consortium Structure and Activities


SESSION TWO: REPORTS OF CONSORTIUM CORE INVESTIGATORS AND SOF PROJECT AWARDEES – PART 1

INSULIN/IGF-1 IN AGING AND LONGEVITY


8:45am - 9:05am Andrzej Bartke and Michal Masternak: Insulin/IGF-1 pathway, diminutive size and longevity in mice

9:05am - 9:35am Elad Ziv: Insulin/IGF-1 signaling pathway genes in human aging and longevity. The challenges of candidate gene analysis in association studies


SESSION TWO: REPORTS OF CONSORTIUM CORE INVESTIGATORS AND SOF PROJECT AWARDEES – PART 2

LONGEVITY IN HUMANS: A NEW AGING GENE IDENTIFICATION STRATEGY IN MICE


10:00am - 10:20am Wen-Chi Hsueh and Richard Cawthon: Telomere length, aging and longevity

10:20am - 10:40am Tim Spector: Telomere shortening in human aging and longevity

10:40am - 11:00am Tom Johnson and Wallace Chick: Stress-resistant embryonic stem cells and the creation of long-lived mice


SESSION TWO: REPORTS OF CONSORTIUM CORE INVESTIGATORS AND SOF PROJECT AWARDEES – PART 3

STRESS RESISTANCE AND AGING


11:00am - 11:20am Alex Reiner: Stress and inflammation genes in human aging and longevity

11:20am - 11:40am Richard Miller: Stress resistance and longevity in mice

11:40am - 12:00pm Greg Tranah and Silvestre Alavez: Heat shock proteins, stress resistance and longevity PART I PART II

12:00pm - 1:30pm Lunch (On Our Own)

Lc Steering Committee & Osmb Meeting: Severn/Potomac Room


SESSION THREE: LONGEVITY ASSOCIATION CORES


1:30pm - 1:50pm Nicholas Schork: The Biostatistics And Bioinformatics Core

1:50pm - 2:10pm Pui Kwok and Ludmila Pawlikowska: The Genomics Core


SESSION FOUR: GENOME WIDE ASSOCIATION WORK-IN-PROGRESS - WHERE DO WE GO FROM HERE?


2:10pm - 2:30pm Teri Manolio: Genome wide association studies at the NIH

2:30pm - 2:50pm Jim Ostell: DbGAP, and NIH database for genome wide association study data

2:50pm - 3:10pm Coffee Break

3:10pm - 3:30pm Joanne Murabito: A Genome-wide association study Of longevity and age-related phenotypes in the Framingham Heart Study

3:30pm - 3:50pm Brad Willcox: Genetic basis for exceptional longevity in Okinawa

3:50pm - 4:10pm Tom Perls: GWA and specific candidate gene studies in centenarians

4:10pm - 4:30pm Gil Atzmon: Longevity Associated Genes In Centenarians

4:30pm - 4:50pm Warren Browner: Coordinating analyses on the genetics of longevity


Meeting Adjourns