May 26-28, 2010
Liaison Capitol Hill Hotel
washington, DC
Consortium Program and Research Activities
Wednesday, May 26, 2010
6:00 PM - 6:45 PM Poster-Reception Session (Cash Bar)
6:45 PM - 7:00 PM Steve Cummings: Opening Remarks and Introduction of Participants
7:00 PM - 7:45 PM Dinner
7:45 PM - 8:30 PM Ian Deary (University of Edinburgh) – Why Do Intelligent Children Live Longer?
Thursday, May 27, 2010
7:00 AM - 8:00 AM Breakfast
8:00 AM - 8:15 AM Steve Cummings – Status of the Consortium and the Competitive Renewal Application
SESSION ONE: PROGRESS REPORTS - LC INVESTIGATORS
8:15 AM - 8:35 AM Richard Miller (U. Michigan): Stress Resistance and Aging in Mice
8:35 AM - 8:55 AM Elad Ziv (UCSF): Insulin/IGF-Signaling Pathway Genes and Human Longevity
8:55 AM - 9:15 AM Poala Sebastiani and Tom Perls (Boston University): Longevity Genes in Centenarians and Super-Centenarians
SESSION TWO: MicroRNAs, AGING AND LONGEVITY
9:15 AM - 9:45 AM Eugenia Wang (U. Louisville): Vital MicroRNA and Target Pairs for Aging and Longevity
9:45 AM - 10:15 AM Monica Driscoll (Rutgers U): MicroRNAs, Molecular insurance for Robustness in Aging?
10:15 AM - 10:30 AM Coffee Break
SESSION THREE: STATE OF THE ART IN GENOME SEQUENCING TECHNOLOGY
10:30 AM - 10:45 AM Pui Kwok (UCSF): Chair and Introductory Remarks
10:45 AM - 11:15 AM Chad Nusbaum (Broad Institute, Boston, MA) – Whole Exome Sequencing: Technology Development, Implementation and Application
11:15 AM - 11:45 PM Elaine Mardis (Washington Universtiy St. Louis): The Technical and Boinformatic challenges of Next-Generation Genomic Sequencing
11:45 PM - 12:05 PM Nik Schork (Scripps, La Jolla, CA): Design and Data Analysis Issues in Sequence-Based Association Studies
12:05 PM - 12:25 PM Joanne Murabito (Boston U, MA): GWAS of Aging Phenotypes within the CHARGE Consortium
12:25 PM - 3:30 PM Lunch (on your own)
Mid-Day Break
3:30 PM - 4:30 PM Poster Session with Wine, Cheese and Coffee
SESSION FOUR: DNA REPAIR, AGING ADN AGE-RELATED DISEASE
4:30 PM - 5:00 PM Francis Rodier (University of Montreal, Canada): The DNA Damage Response Pathways and Inflammatory Secretion
5:00 PM - 5:30 PM Laura Niedernhofer (U. Pittsburgh): DNA Repair Protects Against Numerous Age-Related Degenerative Disease
5:30 PM - 6:00 PM Cynthia T. McMurray (Lawrence Berkeley National Lab): Death by DNA Repair: The Role of Oxidative DNA Damage in Age-Dependent Neurodegeneration
SESSION FIVE: GENE REGULATION IN HUMAN AGING
6:00 PM - 6:20 PM Simon Melov (Buck Institute): Single cell analysis of aging
6:20 PM - 6:40 PM Abraham Aviv (NJSMD): The Genetics and Epigenetics of Human Telomere Biology; a New Paradigm
6:40 PM - 7:00 PM Yair Argon (U. Pennsylvania): Control of IGF production by Human GRP94
MEETING ADJOURNS FOR DAY
Dinner (on your own)
Friday, May 28, 2010
7:30 AM - 8:30 AM: Breakfast
SESSION SIX: STUDIES OF AGING IN SHORT-LIVED VERTEBRATE SPECIES
8:30 AM - 9:00 AM Shuji Kishi (Scripps Institute, FL): Zebrafish as a Genetic Model in Biological and Behavioral Gerontology; Where Development meets Aging in Vertebrates (not confirmed)
9:00 AM - 9:30 AM Dario Riccardo Valenzano (Stanford U): The Short-Lived Fish Notobranchius Furzeri: A New Model System to Study the Genetics of Vertebrate Longevity
SESSION SEVEN: INTERVENTIONS THAT EXPEND LIFESPAN AND HEALTHY AGING
9:30 AM - 10:00 AM Jill Crandall (Albert Einstein): The Effect of Resveratrol on Age-Related Insulin Resistance and Glucose Intolerance
10:00 AM - 10:30 AM Laura Dugan (UCSD): Fullerene Derivatives as Broadly Functional Superoxide Dismutase Mimetics
10:30 AM - 10:50 AM Coffee Break
10:50 AM - 11:10 AM Mahtab Jafari (UC Irvine): Rhodiola rosea, Lifespan and Health Span
11:10 AM - 11:30 AM Richard Miller (U. Michigan): NIA Interventions Testing Program: From NDGA to Resveratrol and Beyond
11:30 AM - 11:50 AM Randy Strong (UTHSC, San Antonio): NIA Interventions Testing Program: Update on Rapamycin
11:50 AM - 12:20 PM Rafael de Cabo (NIA): Life and Health Span Extension in Obese Mice fed Resveratrol and a SIRT 1720